Flexible Filling Solutions for Syringes and Cartridges
Modular designs such as the Bausch+Ströbel VarioSys® allow for component flexibility and product segregation without the expense of separate filling lines. Solutions that enable product adaptability and scale-up without compromising quality are critical, which is why Grand River Aseptic Manufacturing invested in the Bausch+Ströbel VarioSys® flexible filling line with SKAN isolator.
The Features
- Syringes – Nested filling process
- Vials – Bulk filling process (RTU Vials or Bulk)
- Isolator – Connected with the module via inflatable gasket
- Exchangeable modules using “L-flange” technology
The Benefits
- Modular isolator with fast and easily exchangeable filling modules allows rapid changeover (<30 minutes) from one process to another.
- Maintenance, cleaning, and set up of filling modules occurs outside the isolator, thus optimizing filling line utilization.
- Ideal working conditions for processing highly active substances with safe change filter system to ensure containment.
- Optimized decontamination cycle for each module via integrated SKANFOG® technology, which reduces decontamination time.
- Minimizes drug substance (DS) loss and provides maximized batch yields via Bausch+Ströbel ADVANCEDfill zero reject technology.
- Modules can be customized for other activities such as sterile compounding or filling of novel product containers. Larger process equipment can be interfaced with pressure-tight flanges.
GRAM’s VarioSys World
- Learn how GRAM’s flexible filling technology works with sterile injectable products in this 4-part video series: GRAM’s VarioSys World.
VarioSys® Line Overview
